Saturday, September 3, 2011

Carisoprodol Pregnancy and Breastfeeding Warnings

If you become pregnant, contact your doctor. you will need to discuss the benefits and risks using Carisoprodol while you are pregnant. Carisoprodol is found in breast mil. If you are or will be breast-feeding while you use Carisoprodol, check with your doctor. Discuss any possible risks to your baby.

Carisoprodol Pregnancy Warnings

Animal studies have reported reduced testes weight and sperm motility. The significance of these findings for human fertility is unknown.
Carisoprodol has been assigned to pregnancy category C by the FDA. Animal studies have reported that carisoprodol crosses the placenta and results in adverse effects on fetal growth and postnatal survival. However, animal studies have not adequately evaluated the teratogenic effects of carisoprodol. There are no controlled data in human pregnancy. Carisoprodol should only be given during pregnancy when benefit outweighs risk.

Carisoprodol Breastfeeding Warnings

Carisoprodol is excreted into human milk in concentrations two to four times that in the maternal plasma. Adverse effects in nursing infants have not been reported but are theoretically possible. Caution is recommended if carisoprodol is administered to a nursing woman.
In one case report, a breast-fed infant received about 4% to 6% of the maternal daily dose through breast milk and experienced no adverse effects. However, milk production was inadequate and the baby was supplemented with formula. In animal lactation studies, female offspring survival and offspring weight at weaning were decreased. This suggests that maternal use of carisoprodol may lead to reduced or less effective infant feeding (due to sedation) and/or decreased milk production.


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